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Interbilayer forces in membrane fusion : ウィキペディア英語版 | Interbilayer forces in membrane fusion Membrane fusion is a key biophysical process that is essential for the functioning of life itself. It is defined as the event where two lipid bilayers approach each other and then merge to form a single continuous structure.〔Yang et al.,Science,2002,297,1877〕 In living beings, cells are made of an outer coat made of lipid bilayers; which then cause fusion to take place in events such as fertilization, embryogenesis and even infections by various types of bacteria and viruses.〔Jahn et al.,Current Opinion in Cell Biology 2002,14,488〕 It is therefore an extremely important event to study. From an evolutionary angle, fusion is an extremely controlled phenomenon. Random fusion can result in severe problems to the normal functioning of the human body. Fusion of biological membranes is mediated by proteins. Regardless of the complexity of the system, fusion essentially occurs due to the interplay of various interfacial forces, namely hydration repulsion, hydrophobic attraction and van der Waals forces.〔Israelachvili et al.,Biochemistry,1992,31,1794〕 ==Inter-bilayer forces== Lipid bilayers are structures of lipid molecules consisting of a hydrophobic tail and a hydrophilic head group. Therefore, these structures experience all the characteristic Interbilayer forces involved in that regime.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Interbilayer forces in membrane fusion」の詳細全文を読む
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